


Various studies have shown the role of micronutrients in the treatment of female infertility alone and in combination with other treatments. Fortunately, today, it is possible for women to have children via various new therapies such as use of drugs for induction of ovulation (such as clomiphene and gonadotrophins), assisted reproductive technologies (ART), egg and sperm donation, induction of ovulation and micronutrients have made it possible for infertile women to have children (Mascarenhas et al., 2017). Psychosocial disorders caused by this disease include inter personal relationships problems, decreased self‐esteem, feelings of shame, social isolation, risk of harm to mental health, depression, anxiety, despair, guilt, and worthlessness (Abrao et al., 2013).
Vitex and pcos success story skin#
The physical symptoms of this disease include menstrual disorders (no periods, irregular periods, abnormal periods, painful periods, skin changes, changes in sex drive and desire, excessive hair growth (dark hair growth on the lips, chest, and chin) and weight gain. The first category is related to physical disorders caused by infertility, and the second category includes psychosocial disorders. Consequences of infertility in women are classified into two general categories. The most important risk factors are smoking, heavy use of alcohol, chemotherapy or radiation therapy, long‐term use of high‐dosage nonsteroidal anti‐inflammatory drugs (NSAIDs), antipsychotic medications, consumption of recreational drugs such as marijuana and cocaine, obesity, increasing age, and sexually transmitted infections (STIs). These hormonal conditions include polycystic ovary syndrome (PCOS), endometriosis, premature ovarian failure (POF), hypothalamic dysfunction, hyperprolactinemia (too much prolactin), uterine fibroids, and pelvic inflammatory disease (PID) (Mustafa et al., 2019). Female infertility may be caused by an underlying variety of disorders, such as ovulation disorders, damages the fallopian tubes (tubal infertility), cervical disorders (benign polyps or tumors and cervical stenosis), and hormonal imbalances. About 50% of the reasons for infertility in couples are related to female disorders (Vander Borght & Wyns, 2018). One in six couples worldwide suffers from infertility, defined as failure to achieve successful pregnancy after one year of unprotected sex. The compounds in these plants, along with regulating the female endocrine pathways, and improving symptoms of menopause, treat female reproductive disorders such as polycystic ovary syndrome (PCOS), premature ovarian failure (POF), endometriosis, hyperprolactinemia, and hypothalamic dysfunction moreover, because of their anticancer, antioxidant, and antidepressant properties, they can be used in traditional medicine or in the pharmaceutical industry as safe compounds in women's health.

The results of this study showed that different parts of some plants are rich in polyphenolic compounds (isoflavones and flavonoids) and other compounds which are beneficial to in reproductive health in women. In this review, we present some solid evidence for role of herbal medicine in the treatment of female infertility. In this study, using the PRISMA checklist and MeSH keywords, 128 articles were extracted from various databases (PubMed, Cochrane library, WHO, Iranmedex, Science Direct, SID, and Google Scholar search engine) without language and time restrictions, and 128 articles were selected after eliminating duplicate studies. Infertility is defined as the failure to achieve a successful pregnancy after 12 months’ sexual activity that affects 15%–17% of couples in the world and about 50% of them are related to female infertility factors.
